THE SCIENCE
Clarity you can feel
Most energy drinks and coffees spike your system, then drop you flat. ThinkDrink gives your brain real energy at the cellular level, no crash, just clean clarity that lasts.
Our ingredients
Matcha - antioxidants for clean, balanced alertness
Our premium matcha green tea is sourced from trusted, organic farms in Japan, where the leaves are carefully harvested from early spring plants to ensure maximum flavor and potency. Known for its vibrant green color and rich taste, this matcha is of the highest culinary grade, making it a versatile superfood.
Matcha is renowned for its thermogenic properties, helping to boost metabolism and support healthy immune function. Rich in L-theanine, an amino acid that stimulates the production of serotonin and dopamine, matcha promotes a calm, focused energy. Its powerful antioxidants also work to combat premature aging, while the high levels of chlorophyll help to cleanse and detoxify the blood and tissues, contributing to overall well-being.
Lion's Mane - supports memory and learning
Lion’s Mane is supported by a groundbreaking human clinical trial, showcasing its acute (single-dose) cognitive benefits, with impressive results observed as early as one hour post-ingestion. Rich in β-glucan polysaccharides, proteins, hericenones, and erinacines, this powerful mushroom extract is renowned for its nootropic effects.
Acute Benefits of Lion’s Mane Extract:
• Enhances attention, focus, and working memory
• Elevates mood and emotional well-being
• Sharpens reaction time and mental processing speed
• Supports a balanced and resilient immune system
Reishi - promotes calm focus
Renowned for centuries as “The Mushroom of Immortality,” Reishi mushroom has long been celebrated for its ability to enhance vitality and promote overall wellness. Esteemed in traditional Eastern medicine, Reishi extract is regarded as a potent "super adaptogen" that helps the body adapt to stress, improves sleep quality, and supports a balanced immune system.
Benefits of Reishi Extract:
• Promotes relaxation and supports a balanced nervous system
• Enhances sleep quality for restful, rejuvenating nights
• Fosters emotional well-being and stabilizes mood, helps regulate and strengthen immune function
Creatine - energy for brain and body
Creatine monohydrate is one of the most extensively studied supplements, known for its role in helping cells replenish ATP—the energy source that powers the body’s muscles and brain.
Research on creatine now extends beyond physical performance. A 2024 review of clinical trials found improvements in memory and information-processing speed, adding to growing research on creatine and brain function. Researchers are also exploring creatine’s potential role in bone health, including bone density and strength, particularly alongside resistance training.
Together, these areas of research make creatine a compelling ingredient for supporting cellular energy throughout the body.
Organic Lemon Powder - enhances flavor
Simple, just real lemons….no other filler or flavor enhancing substitutes, organic lemon powder brings a bright, natural citrus character to the blend. It helps complement the refreshing flavor of ThinkDrink while offering a convenient powdered form of this familiar fruit.
Key attributes:
- Organic
- Citrus-derived
- Flavor-enhancing
Organic Pure Stevia - for a natural sweetness
100% Pure Stevia powder is made with no fillers or additives and gives a natural sweetness with no spike to blood glucose levels! This Zero-Calorie, plant-based sweetener is perfect for those following gluten-free, vegan, or keto diets. By using pure Stevia, we can use very little sweetener to achieve a wonderful taste while remaining last on our ingredient list due to how little is used.
Key attributes:
- Plant-derived
- Sweetens without conventional sugar
- Low-calorie sweetener
Organic Pure Monk Fruit - adds a honey-like sweetness
100% Pure Monk Fruit with No Erythritol or other fillers has been one of our favorite finds while looking for ingredients for ThinkDrink! It leaves a wonderful honey note to complement the rest of the ingredients all while being naturally Zero-Calorie and Sugar-Free. Monk fruit has been used for centuries and is a sweetener that actually brings health to your body. Enjoy sweetness and feel good about it... literally!
Key attributes:
- All Natural Fruit
- Plant-based sweetener
- Sugar-Free
- Zero-Calorie
- Vegan
- Gluten-Free
- Paleo
Acacia Gum - adds dietary fiber
Acacia gum is a soluble dietary fiber derived from the sap of the acacia tree. It can help contribute dietary fiber to a beverage formulation while offering a mild taste and good versatility in powdered drink mixes.
Key attributes:
- Plant-derived
- Soluble dietary fiber
- Mild taste
Citric Acid - balances flavor for a refreshing taste
Citric acid is an organic acid naturally found in citrus fruits and widely used in food and beverages. It helps balance sweetness, enhance citrus notes, and maintain a crisp, refreshing flavor in ThinkDrink.
Key attributes:
- Acidity regulator
- Flavor balancing
- Supports a refreshing taste
p39 Nutritional's Scientific Advisory Board
Our Scientific Advisory Board (SAB) brings together experienced professionals who provide scientific insight, expert perspectives, and strategic guidance. Their role is to help inform product innovation, evaluate emerging research, and support p39 Nutritionals’ commitment to science-driven nutrition, quality, and wellness.
Meet
Dr. Harry H. Black
Dr.Black serves on the Scientific Advisory Board of p39nutritionals, bringing more than four decades of experience in medicine, surgery, cancer care, and physician-led health and wellness education. From Surgeon to Survivor to Wellness Advocate. Board-certified general and trauma surgeon with over 40 years of experience, 15,000+ surgeries performed, and 75,000+ patients treated.
Now dedicated to helping others achieve optimal health through physician-ledcancer education in Ormond Beach, Florida.
40+ Years of Surgical Excellence
Dr. Black is a board-certified general and trauma surgeon with over four decades of experience, having performed more than 15,000 surgeries and treated over 75,000 patients throughout his distinguished career. His expertise spans the full spectrum of general and trauma surgery, with particular depth in cancer treatment and complex abdominal procedures.
When the Surgeon Became the Patient
In a life-altering turn, Dr. Black was diagnosed with prostate cancer. This experience transformed his perspective on patient care forever. He understood - for the first time from the other side - what it truly means to face a cancer diagnosis, navigate treatment decisions, and seek not just survival, but thriving recovery.
This deeply personal journey sparked a new mission: to create the comprehensive wellness support system he wished had existed during his own treatment.
Meet
Jeanne Tregilgas
Jeanne Tregilgas serves as Chief Operating Officer at Believe Big Institute of Health, where she helps lead strategic growth, operational development, and the
expansion of integrative health services.
Previously, she served as a Clinic Nutritionist at Zuza’s Way Integrative Care, specializing in metabolic health, nutrigenomics, and metabolic oncology. In this role, she worked directly with clients to translate complex nutritional
and functional health concepts into practical, individualized strategies, supporting those navigating complex metabolic and oncologic conditions.
Her approach to care is grounded in the belief that nutrition should be personalized, evidence-informed, and viewed within the broader context of an individual’s health and physiology.
Jeanne is a Board Certified Integrative and Functional Nutrition Practitioner through the Integrative and Functional Nutrition Academy. She holds a Bachelor of Science in Kinesiology, Health and Sport Science from Indiana University of Pennsylvania, along with a minor in Business Administration
Frequently Asked Questions
Who is ThinkDrink designed for?
ThinkDrink Brain Boost is designed for a wide range of individuals, including adults, teenagers, children (with proper supervision), athletes, students, professionals, and anyone looking to support brain health, muscle strength, mental wellness and clarity and bone density including anti-inflammatory and anti-cramping benefits. Always consult a healthcare professional before starting any supplement regimen.
Is ThinkDrink safe for children?
ThinkDrink contains ingredients that have been studied for safety in children, particularly for brain health. We recommend considering ThinkDrink for children only after confirming the safety and suitability of its nine ingredients.
Can ThinkDrink support anxiety, depression, and sleep deprivation?
ThinkDrink is thoughtfully formulated to support healthy brain energy levels, reduce oxidative stress, and promote overall mental wellness. Key ingredients such as Reishi mushroom are traditionally known for their calming, adaptogenic properties, which may help the body manage stress, while Lion’s Mane mushroom is studied for its potential to support cognitive function and enhance mood through its effects on neurogenesis. Although these ingredients may help promote resilience to stress, sleep deprivation, and low mood, ThinkDrink is not intended to diagnose, treat, cure, or prevent depression or any other medical condition. Individual results may vary, and we recommend consulting a healthcare provider for personalized advice.
How does ThinkDrink support bone density?
Emerging research suggests that key ingredients in ThinkDrink may help support bone strength, particularly with consistent use over time. Ongoing studies are currently evaluating the potential impact of these ingredients on conditions such as osteoporosis, and we will update this information as new findings become available. These benefits may be especially relevant for women and aging adults. As with any supplement, individual results may vary.
Can I heat ThinkDrink?
Yes, ThinkDrink can be added to warm beverages without significantly affecting its efficacy. However, prolonged exposure to temperatures above 170°F may compromise the stability of certain ingredients.
Does ThinkDrink cause high blood pressure?
There is no evidence to suggest that the ingredients in ThinkDrink cause elevated blood pressure in healthy individuals. Always consult your healthcare provider if you have concerns.
Does ThinkDrink cause mood swings?
No. In fact, ThinkDrink is formulated to support balanced brain energy metabolism, which may assist in promoting emotional stability.
Is ThinkDrink beneficial for women?
Absolutely. ThinkDrink supports bone density, brain health, hormonal balance, and muscle recovery, making it an excellent choice for women of all ages.
How much ThinkDrink is needed for brain health benefits?
For optimal cognitive support, consistent daily use is recommended. Some research suggests that a loading phase with higher amounts may produce quicker effects, but ThinkDrink is formulated for ease of daily use without the need for excessive dosing.
Can ThinkDrink help with sleep deprivation and brain fog?
ThinkDrink may help support mental clarity and cognitive resilience during periods of sleep deprivation by promoting healthy brain energy metabolism. However, it is not intended to replace sleep.
Does the creatine monohydrate in ThinkDrink cause hair loss?
No. There is no scientific evidence to suggest that the creatine monohydrate or any other ingredients in ThinkDrink are associated with hair loss. Extensive clinical research has not demonstrated any direct correlation between creatine supplementation and hair loss.
Does ThinkDrink cause water retention?
The 4 grams of creatine monohydrate in ThinkDrink are not typically associated with water retention or weight fluctuations. While mild water retention may occur in some individuals during a higher-dose loading phase (e.g., 20 grams or more), consistent use of 4 grams per day is generally not linked to significant changes in body weight. In fact, emerging research suggests that regular creatine use may help reduce body fat over time. Any mild water retention should be viewed as part of enhanced muscle hydration, which can help reduce cramping, promote healthy hydration, and support muscle performance—without being confused with fat gain.
Is ThinkDrink safe for long-term use?
ThinkDrink is formulated with ingredients that have been extensively studied for safety in long-term use. As always, we recommend regular consultation with your healthcare provider to ensure the product aligns with your individual health needs and goals.
Does ThinkDrink contain caffeine?
Yes. ThinkDrink Matcha flavor contains approximately 60–70 mg of naturally occurring caffeine per serving.
Does caffeine interact with ThinkDrink?
Excessive caffeine intake (above 250 mg) may reduce the efficacy of creatine monohydrate in ThinkDrink. To optimize benefits, we recommend spacing the consumption of ThinkDrink and high-caffeine beverages by 90 to 120 minutes.
Has ThinkDrink been third-party tested?
Yes. ThinkDrink has undergone extensive third-party testing before and after manufacturing for heavy metals, yeast, mold, and microbial counts to ensure product purity and safety.
Can I take ThinkDrink with food?
Yes, you can! Taking ThinkDrink with food-especially when you're first introducing it to your system-can help your body process the natural ingredients more comfortably and reduce the chance of irritation.
Citations
- Zhang, C.-C.; Cao, C.-Y.; Kubo, M.; Harada, K.; Yan, X.-T.; Fukuyama, Y.; Gao, J.-M. Chemical Constituents from Hericium Erinaceus Promote Neuronal Survival and Potentiate Neurite Outgrowth via the TrkA/Erk1/2 Pathway. Int. J. Mol. Sci. 2017, 18, 1659.
- La Monica MB, Raub B, Ziegenfuss EJ, Hartshorn S, Grdic J, Gustat A, Sandrock J, Ziegenfuss TN. Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion’s Mane Extracts on Cognitive Performance. Nutrients. 2023 Dec 6;15(24):5018.
- Brandalise, F.; Roda, E.; Ratto, D.; Goppa, L.; Gargano, M.L.; Cirlincione, F.; Priori, E.C.; Venuti, M.T.; Pastorelli, E.; Savino, E.; et al. Hericium Erinaceus in Neurodegenerative Diseases: From Bench to Bedside and Beyond. J. Fungi 2023, 9, 551.
- Saitsu, Y.; Nishide, A.; Kikushima, K.; Shimizu, K.; Ohnuki, K. Improvement of Cognitive Functions by Oral Intake of Hericium Erinaceus. Biomed. Res. 2019, 40, 125–131.
- Grozier, C.D.; Alves, V.A.; Killen, L.G.; Simpson, J.D.; O’neal, E.K.; Waldman, H.S. Four Weeks of Hericium Erinaceus Supplementation Does Not Impact Markers of Metabolic Flexibility or Cognition. Int. J. Exerc. Sci. 2022, 15, 1366.